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Biological Activity
MIM1 is a selective small molecule inhibitor of Mcl-1(IC50= 4.8 μM) that overcomes Mcl-1-dependent leukemia cell survival.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.78 mL | 143.91 mL | 287.83 mL |
| 0.5 mM | 5.76 mL | 28.78 mL | 57.57 mL |
| 1 mM | 2.88 mL | 14.39 mL | 28.78 mL |
| 5 mM | 0.58 mL | 2.88 mL | 5.76 mL |
*The above data is based on the productmolecular weight 347.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16315 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 509102-00-5 |
| Formula | C17H21N3O3S |
| M. Wt | 347.43 |
| Purity | >98% |
| Synonyms | MIM 1, MIM-1, Inhibitor of Mcl-1 |
| SMILES | OC1=CC=C(/C=N/N2C(C)=CS/C2=N\C3CCCCC3)C(O)=C1O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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