Fig. 1 · Structure
Documents & Downloads
MIND4
SIRT2 Inhibitor
MIND4 is a selective SIRT2 inhibitor known for its neuroprotective properties. This thiozoline compound also functions as an inducer and activator of the nuclear factor NRF2, promoting antioxidant responses. MIND4 effectively induces NRF2 activation in both neuronal and non-neuronal cells, leading to a decrease in reactive oxygen and nitrogen species production. This makes MIND4 a valuable tool for research focusing on neuroprotection and oxidative stress responses.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1639965-26-6 |
| Applications | SIRT2 Inhibitor |
| Formula | C24H17N5O3S |
| Molecular Weight | 455.49 |
| SMILES | O=[N+]([O-])C1=C2C=CC=NC2=C(C=C1)SC3=NN=C(N3C4=CC=CC=C4)COC5=CC=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.