Minocycline-d6 is a deuterium-labeled form of Minocycline, a semi-synthetic tetracycline antibiotic known for its ability to penetrate the blood-brain barrier. It acts primarily as a hypoxia-inducible factor (HIF)-1α inhibitor and exhibits anti-cancer, anti-inflammatory, and glutamate antagonistic properties. The compound effectively reduces glutamate neurotransmission, offering neuroprotective and antidepressant effects. Additionally, Minocycline inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome, producing a bacteriostatic effect. This reagent is suitable for research in pharmacology, neuroscience, and cancer biology.
Minocycline-d6 is a deuterium-labeled form of Minocycline, a semi-synthetic tetracycline antibiotic known for its ability to penetrate the blood-brain barrier. It acts primarily as a hypoxia-inducible factor (HIF)-1α inhibitor and exhibits anti-cancer, anti-inflammatory, and glutamate antagonistic properties. The compound effectively reduces glutamate neurotransmission, offering neuroprotective and antidepressant effects. Additionally, Minocycline inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome, producing a bacteriostatic effect. This reagent is suitable for research in pharmacology, neuroscience, and cancer biology.
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