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Minocycline-d6

Stable Isotope

Minocycline-d6 is a deuterium-labeled form of Minocycline, a semi-synthetic tetracycline antibiotic known for its ability to penetrate the blood-brain barrier. It acts primarily as a hypoxia-inducible factor (HIF)-1α inhibitor and exhibits anti-cancer, anti-inflammatory, and glutamate antagonistic properties. The compound effectively reduces glutamate neurotransmission, offering neuroprotective and antidepressant effects. Additionally, Minocycline inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome, producing a bacteriostatic effect. This reagent is suitable for research in pharmacology, neuroscience, and cancer biology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1036070-10-6
Applications	Stable Isotope
Formula	C₂₃H₂₁D₆N₃O₇
Molecular Weight	463.51
SMILES	O[C@]12[C@](C[C@@]3([H])C(C(C4=C(O)C=CC(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=C4C3)=O)=C2O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.