Fig. 1 · Structure

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Mip-IN-1

Mip Inhibitor

Mip-IN-1 (S,S-28i) is a potent inhibitor of macrophage infectivity potentiator (Mip) proteins, specifically targeting Neisseria meningitidis and Neisseria gonorrhoeae. It demonstrates robust anti-enzymatic activity, enhancing the capability of macrophages to effectively eliminate these bacterial pathogens. This compound is valuable for investigating macrophage-bacteria interactions and developing therapeutic strategies against infections caused by these Neisseria species.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2984599-57-5
Applications Mip Inhibitor
Formula C27H29FN4O4S
Molecular Weight 524.61
SMILES
O=C([C@@H](NC([C@H]1N(CCCC1)S(=O)(CC2=CC=CC=C2)=O)=O)C3=CC=C(C=C3)F)NCC4=CN=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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