Fig. 1 · Structure
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Mipomersen sodium
apoB Inhibitor
Mipomersen sodium is an antisense oligonucleotide targeting apolipoprotein B (apoB), effectively inhibiting its expression. This compound has demonstrated potential anti-hepatitis C virus (HCV) activity by reducing the infectivity of HCV. Mipomersen sodium is primarily utilized in research focused on homozygous familial hypercholesterolemia (HoFH), contributing to a deeper understanding of lipid metabolism and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 629167-92-6 |
| Applications | apoB Inhibitor |
| Molecular Weight | 7179.15 (free acid) |
| Synonyms | ISIS 301012 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.