Fig. 1 · Structure
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Mipomersen
apoB Inhibitor
Mipomersen is an antisense oligonucleotide that specifically inhibits apolipoprotein B (apoB) synthesis. This compound is primarily utilized in research focused on homozygous familial hypercholesterolemia (HoFH), demonstrating significant efficacy in lipid regulation. Additionally, Mipomersen exhibits anti-hepatitis C virus (HCV) activity, contributing to reduced infectivity of the virus. Its unique mechanism makes it a valuable tool for studying lipid disorders and viral infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1000120-98-8 |
| Applications | apoB Inhibitor |
| Molecular Weight | 7179.15 |
| Synonyms | ISIS 301012 free base |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.