Fig. 1 · Structure
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Miro1 Reducer
Miro1 Reducer
Miro1 Reducer is a small molecule designed to decrease Miro1 protein levels, thereby targeting the underlying defects associated with Parkinson's disease. It effectively reduces the delayed mitophagy phenotype observed in fibroblasts derived from patients with Parkinson's disease in a dose-dependent manner, with an IC50 value of 7.8 mM. This compound is valuable for research into the mechanisms of mitophagy and the pathophysiology of neurodegenerative disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2624336-91-8 |
| Applications | Miro1 Reducer |
| Formula | C20H17ClFN7O |
| Molecular Weight | 425.85 |
| SMILES | O=C(NC1=CC(F)=CC=C1)NC2=CC=C(NC3=NC=NC(N4C=NC=C4)=C3)C=C2.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.