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MitoBloCK-1

Inhibitor That Blocks TIM22-mediated Substrate Import

MitoBloCK-1 is a potent inhibitor that targets the TIM22 import pathway by preventing substrate binding to the Tim9/10 complex. This mechanism effectively disrupts the translocation of TIM22 substrates into mitochondria, inhibiting the import of key carrier proteins, including ADP/ATP and phosphate carriers, as well as the outer membrane protein Tom40. MitoBloCK-1 is valuable for research into mitochondrial function and the role of protein import mechanisms in cellular metabolism.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	373370-73-1
Applications	Inhibitor That Blocks TIM22-mediated Substrate Import
Formula	C₁₄H₁₄BrN₃O₂S
Molecular Weight	368.25
Synonyms	MB-1
SMILES	S=C(N/N=C/C1=C2C(CCCC3)=C3OC2=CC(Br)=C1O)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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MitoBloCK-1

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MitoBloCK-1 5 mg