Fig. 1 · Structure
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MitoEbselen-2 chloride
Radiation Mitigator
MitoEbselen-2 chloride, a mitochondria-targeted mimic of glutathione peroxidase, functions primarily as a radiation mitigator. This compound exhibits potent antioxidant activity by reducing lipid hydroperoxides, thereby protecting cells from oxidative stress-induced apoptotic cell death. It is utilized in research applications related to radiation protection and mitochondrial function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1638973-78-0 |
| Applications | Radiation Mitigator |
| Formula | C35H30ClN2O2PSe |
| Molecular Weight | 656.01 |
| Synonyms | MitoPeroxidase 2 |
| SMILES | O=C(NCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)CC4=CC=C(N5[Se]C6=C(C=CC=C6)C5=O)C=C4.[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.