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Biological Activity
Mitoxantrone is a synthetic antineoplastic anthracenedione (IC50 = 0.42 mM).
Targets
| Topo II (Cell-free assay) | ||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.5 mL | 112.49 mL | 224.97 mL |
| 0.5 mM | 4.5 mL | 22.5 mL | 44.99 mL |
| 1 mM | 2.25 mL | 11.25 mL | 22.5 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.5 mL |
*The above data is based on the productmolecular weight 444.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10595 |
|---|---|
| CAS No. | 65271-80-9 |
| Formula | C22H28N4O6 |
| M. Wt | 444.5 |
| Purity | >98% |
| SMILES | C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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