Fig. 1 · Structure
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MK-0343
GABA(A) Receptor Agonist
MK-0343 is an orally bioavailable partial agonist selective for the GABA(A) receptor subtype. This compound exhibits anxiolytic properties without sedation, making it a valuable tool for neurological research. MK-0343 is utilized in studies involving anxiety disorders and the modulation of neurotransmitter systems, contributing to the understanding of therapeutic approaches for related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Partial Agonist |
| CAS Number | 233275-76-8 |
| Applications | GABA(A) Receptor Agonist |
| Formula | C19H17F2N7O |
| Molecular Weight | 397.38 |
| Synonyms | MRK-409 |
| SMILES | CN1N=CN=C1COC2=NN3C(C=C2C4CCC4)=NN=C3C5=C(F)C=CC=C5F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.