MK-0489

Name: MK-0489
Brand: Adooq Bioscience
SKU: A61702
Rating: 5 (288 reviews)

Catalog No.: A61702

MC4R Agonist

MK-0489 is a selective agonist targeting the melanocortin-4 receptor (MC4R). Demonstrating a strong binding affinity with an IC50 of 13 nM and functional activity characterized by an EC50 of 4.6 nM in human MC4R, it also exhibits an EC50 of 22 nM for mouse MC4R and 1.7 μM for mouse MC3R. This compound is valuable for research applications focused on obesity and related metabolic disorders.

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
Size	Stock
5mg	Please Inquiry
10mg	Please Inquiry
50mg	Please Inquiry
Bulk Size	Bulk Discount

Bulk Inquiry

Notify me when the price drops

Notify me when this product is in stock

Free Delivery on orders over $500

Research use only. We do not sell to patients.

Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper

Biological Activity

Description	MK-0489 is a selective agonist targeting the melanocortin-4 receptor (MC4R). Demonstrating a strong binding affinity with an IC50 of 13 nM and functional activity characterized by an EC50 of 4.6 nM in human MC4R, it also exhibits an EC50 of 22 nM for mouse MC4R and 1.7 μM for mouse MC3R. This compound is valuable for research applications focused on obesity and related metabolic disorders.

Product Information

Catalog Num	A61702
Formula	C34H44ClF2N3O2
Molecular Weight	600.18
CAS Number	778625-65-3
SMILES	CC(NC(C)([C@@H]1CC2(CCN(C([C@@H]3CN(C(C)(C)C)C[C@H]3C4=CC=C(F)C=C4F)=O)CC2)C5=C1C=C(C)C(Cl)=C5)C)=O

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂