MK-0493

Catalog No.: A61634
MC4R Agonist
MK-0493 is an orally active agonist of the melanocortin-4 receptor (MC4R), known for its role in regulating appetite and energy balance. This compound is demonstrated to reduce food intake and suppress weight gain, while also elevating blood pressure at elevated doses. Additionally, MK-0493 displays preclinical activity in erectile function regulation, making it a valuable tool in obesity and metabolic disorder research.
Grouped product items
Size Price Stock Qty
1mg
$155.00
In stock
5mg
$355.00
In stock
10mg
$580.00
In stock
25mg
$1,780.00
In stock
50mg
$2,280.00
In stock
100mg
$2,960.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMK-0493 is an orally active agonist of the melanocortin-4 receptor (MC4R), known for its role in regulating appetite and energy balance. This compound is demonstrated to reduce food intake and suppress weight gain, while also elevating blood pressure at elevated doses. Additionally, MK-0493 displays preclinical activity in erectile function regulation, making it a valuable tool in obesity and metabolic disorder research.
Product Information
Catalog NumA61634
FormulaC30H38ClF2N3O2
Molecular Weight546.09
CAS Number455956-93-1
SMILESCC(N[C@@H](C)C1=CC(Cl)=CC=C1C2CCN(CC2)C([C@@H]3CN(C[C@H]3C4=CC=C(C=C4F)F)C(C)(C)C)=O)=O
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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