Fig. 1 · Structure
Documents & Downloads
MK-0493
MC4R Agonist
MK-0493 is an orally active agonist of the melanocortin-4 receptor (MC4R), known for its role in regulating appetite and energy balance. This compound is demonstrated to reduce food intake and suppress weight gain, while also elevating blood pressure at elevated doses. Additionally, MK-0493 displays preclinical activity in erectile function regulation, making it a valuable tool in obesity and metabolic disorder research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 455956-93-1 |
| Applications | MC4R Agonist |
| Formula | C30H38ClF2N3O2 |
| Molecular Weight | 546.09 |
| SMILES | CC(N[C@@H](C)C1=CC(Cl)=CC=C1C2CCN(CC2)C([C@@H]3CN(C[C@H]3C4=CC=C(C=C4F)F)C(C)(C)C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.