Fig. 1 · Structure
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MK-0608
HCV Replication Inhibitor
MK-0608 is a potent, orally bioavailable inhibitor targeting hepatitis C virus (HCV) replication. It demonstrates significant antiviral activity with an effective concentration (EC50) of 0.3 μM and an EC90 of 1.3 μM in subgenomic replicon assays. This compound is valuable for research applications focused on the mechanisms of HCV replication and the development of antiviral therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 443642-29-3 |
| Applications | HCV Replication Inhibitor |
| Formula | C12H16N4O4 |
| Molecular Weight | 280.28 |
| SMILES | OC[C@@H]1[C@@H](O)[C@](O)(C)[C@H](N2C=CC3=C2N=CN=C3N)O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.