Cellular Effect
| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| CV-1 | EC50 | 144 nM | Agonist activity at human AR expressed in African green monkey CV1 cells after 17 hrs by ARE-driven luciferase reporter gene assay | 10.1039/C3MD20341G |
Fig. 1 · Structure
Documents & Downloads
MK-0773
Cat. No.
A15164
CAS
606101-58-0
Androgen receptor modulator
MK-0773, one of selective androgen receptor modulators (SARMs), is a 4-aza-steroid that exhibited tissue selectivity in humans (IC50= 6.6 nM).
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 606101-58-0 |
| Applications | Androgen receptor modulator |
| Formula | C27H34FN5O2 |
| Molecular Weight | 479.59 |
| Synonyms | PF 05314882 |
| SMILES | CC12CCC3C(C1CCC2C(=O)NCC4=NC5=C(N4)C=CC=N5)CCC6C3(C=C(C(=O)N6C)F)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.