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MK-251

Anti-arrhythmic Agent

MK-251 is an orally active anti-arrhythmic agent that primarily targets cardiac activity to prevent or modify ventricular arrhythmias. It has been shown to antagonize arrhythmias induced by tetrafluorethylbutylamine in animal models, as well as those caused by digoxin in felines. At effective therapeutic doses, MK-251 exhibits minimal impact on fundamental cardiovascular parameters such as blood pressure, cardiac output, myocardial contractility, and ventricular conduction, highlighting its distinct therapeutic profile. This compound is of interest for cardiovascular research and the study of arrhythmias.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	36386-71-7
Applications	Anti-arrhythmic Agent
Formula	C₁₇H₁₇F₄N
Molecular Weight	311.32
SMILES	FC(C1=CC=CC=C1)(C(F)(C2=CC=C(C(C)(C)N)C=C2)F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.