MK-3168 (12C) is a potent FAAH inhibitor exhibiting IC50 values of 1.0 nM for human, 5.5 nM for rhesus, and 1.7 nM for rat models. This compound demonstrates significant brain uptake and produces a FAAH-specific signal, making it a valuable tool in neurobiological research. MK-3168 (12C) is also applicable as a PET tracer for studying FAAH activity in vivo, facilitating insights into cannabinoid signaling pathways.
MK-3168 (12C) is a potent FAAH inhibitor exhibiting IC50 values of 1.0 nM for human, 5.5 nM for rhesus, and 1.7 nM for rat models. This compound demonstrates significant brain uptake and produces a FAAH-specific signal, making it a valuable tool in neurobiological research. MK-3168 (12C) is also applicable as a PET tracer for studying FAAH activity in vivo, facilitating insights into cannabinoid signaling pathways.
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