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CGRP Receptor antagonist

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Catalog No. A15165

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MK-3207 10mg A15165-10
MK-3207 25mg A15165-25
MK-3207 50mg A15165-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC50= 0.12 nM; Ki value= 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3.


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Chemical Information

Catalog Num A15165
Actions Antagonist
M. Wt 557.59
Formula C31H29F2N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 957118-49-9
Synonyms MK3207, MK 3207
SMILES C1CCC2(C1)C(=O)N(C(CN2)C3=CC(=CC(=C3)F)F)CC(=O)NC4=CC5=C(CC6(C5)C7=C(NC6=O)N=CC=C7)C=C4

Biological Activity

MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC50= 0.12 nM; Ki value= 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.93 mL 89.67 mL 179.34mL
0.5 mM 3.59 mL 17.93 mL 35.87 mL
1 mM 1.79 mL 8.97 mL 17.93 mL
5 mM 0.36 mL 1.79 mL 3.59 mL

*The above data is based on the productmolecular weight 557.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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