Fig. 1 · Structure
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MK-4965
NNRTI
MK-4965 is a nonnucleoside reverse transcriptase inhibitor (NNRTI) that exhibits potent antiviral activity against HIV-1 wild-type strains as well as a diverse array of NNRTI-resistant variants. This compound is utilized in research studies focused on HIV-1 infection, enabling the exploration of resistance mechanisms and the development of effective therapeutic strategies. MK-4965 serves as a valuable tool in the investigation of HIV-1 reverse transcription processes and antiviral drug design.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 920035-77-4 |
| Applications | NNRTI |
| Formula | C20H13Cl2N5O2 |
| Molecular Weight | 426.26 |
| SMILES | N#CC1=CC(Cl)=CC(OC2=CC(OCC3=NNC4=NC(N)=CC=C43)=CC=C2Cl)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.