MK-571 sodium salt

Catalog No.: A15983

CysLT1 receptor antagonist

MK-571 sodium salt

MK-571 sodium salt Chemical Structure

CAS NO. 115103-85-0

MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$45.00
10 mg
$80.00
50 mg
$320.00
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Biological Activity

MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively.
Targets
CysLT1 MRP1 MRP4 cMOAT
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.62 mL 93.1 mL 186.2 mL
0.5 mM 3.72 mL 18.62 mL 37.24 mL
1 mM 1.86 mL 9.31 mL 18.62 mL
5 mM 0.37 mL 1.86 mL 3.72 mL

*The above data is based on the productmolecular weight 537.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15983
Actions Antagonist
CAS No. 115103-85-0
Formula C26H26ClN2NaO3S2
M. Wt 537.06
Purity >98%
Synonyms L-660,711, L660,711, L 660,711, L-660711
SMILES O=C([O-])CCSC(C1=CC=CC(/C=C/C2=NC3=CC(Cl)=CC=C3C=C2)=C1)SCCC(N(C)C)=O.[Na+]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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