Fig. 1 · Structure
Documents & Downloads
MK-7288
H3 Receptor Inverse Agonist
MK-7288 is a histamine H3 receptor inverse agonist that modulates neurotransmitter release to enhance wakefulness. It has demonstrated the ability to prolong sleep latency in the Maintain Wake Test (MWT), making it a valuable tool in the investigation of obstructive sleep apnea (OSA) and excessive daytime sleepiness (EDS). This compound is essential for researchers exploring sleep regulation and associated disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inverse Agonist |
| CAS Number | 936626-07-2 |
| Applications | H3 Receptor Inverse Agonist |
| Formula | C22H31N3O4 |
| Molecular Weight | 401.50 |
| SMILES | O=C([C@@H]1CC[C@]2(C3=CC=C(OC)N=C3C(O2)=O)CC1)N(C)CCN4CCCCC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.