MK-8745
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | MK-8745 is a novel Aurora-A specific inhibitor. It induces apoptotic cell death in a p53-dependent manner when tested in vitro in cell lines of multiple lineages. | ||
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Catalog Num | A13396 |
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Formula | C20H19ClFN5OS |
Molecular Weight | 431.91 |
CAS Number | 885325-71-3 |
SMILES | ClC1=C(F)C(C(N2CCN(CC3=NC(NC4=NC=CS4)=CC=C3)CC2)=O)=CC=C1 |
Synonyms | MK8745, MK 8745 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 81 mg/mL (187.53 mM) | |
Water | Insoluble | ||
Ethanol | 1 mg/mL (2.31 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.15 mL | 115.76 mL | 231.53 mL |
0.5 mM | 4.63 mL | 23.15 mL | 46.31 mL |
1 mM | 2.32 mL | 11.58 mL | 23.15 mL |
5 mM | 0.46 mL | 2.32 mL | 4.63 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2