Catalog No.: A12508

IRE1α inhibitor


MKC3946 Chemical Structure

CAS NO. 1093119-54-0

MKC3946 is a potent and soluble IRE1α inhibitor, used for cancer research.

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

MKC3946 is a potent and soluble IRE1α inhibitor, used for cancer research.
In vitro DMSO 35 mg/mL (91.99 mM)
Water Insoluble
Ethanol 3 mg/mL (7.88 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.28 mL 131.42 mL 262.84 mL
0.5 mM 5.26 mL 26.28 mL 52.57 mL
1 mM 2.63 mL 13.14 mL 26.28 mL
5 mM 0.53 mL 2.63 mL 5.26 mL

*The above data is based on the productmolecular weight 380.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12508
Actions Inhibitor
CAS No. 1093119-54-0
Formula C21H20N2O3S
M. Wt 380.46
Purity >98%
Synonyms MKC 3946, MKC-3946

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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