ML-00253764 hydrochloride is a nonpeptidic antagonist of the melanocortin receptor 4 (MC4R), demonstrating a Ki of 0.16 μM and an IC50 of 0.103 μM. This compound effectively penetrates the blood-brain barrier, making it suitable for central nervous system studies. Its antagonistic activity at MC4R suggests potential applications in obesity research and metabolic disorder investigations.
ML-00253764 hydrochloride is a nonpeptidic antagonist of the melanocortin receptor 4 (MC4R), demonstrating a Ki of 0.16 μM and an IC50 of 0.103 μM. This compound effectively penetrates the blood-brain barrier, making it suitable for central nervous system studies. Its antagonistic activity at MC4R suggests potential applications in obesity research and metabolic disorder investigations.
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