Fig. 1 · Structure
Documents & Downloads
ML 083
Cat. No.
A77427
CAS
562867-96-3
hPK-M2 Activator
ML083 is a selective allosteric activator for the tumor-specific isoform of human pyruvate kinase (PK-M2). By modulating the cooperativity of phosphoenolpyruvate (PEP) binding, ML083 enhances PK-M2 activity, making it a valuable tool for studying tumor metabolism. This compound is essential for research applications focusing on cancer biology and metabolic regulation within tumor cells.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 562867-96-3 |
| Applications | hPK-M2 Activator |
| Formula | C19H22N2O7S2 |
| Molecular Weight | 454.52 |
| Synonyms | BML283 |
| SMILES | O=S(N1CCN(S(=O)(C2=CC=C(OCCO3)C3=C2)=O)CC1)(C4=CC=C(OC)C=C4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.