ML083 is a selective allosteric activator for the tumor-specific isoform of human pyruvate kinase (PK-M2). By modulating the cooperativity of phosphoenolpyruvate (PEP) binding, ML083 enhances PK-M2 activity, making it a valuable tool for studying tumor metabolism. This compound is essential for research applications focusing on cancer biology and metabolic regulation within tumor cells.
ML083 is a selective allosteric activator for the tumor-specific isoform of human pyruvate kinase (PK-M2). By modulating the cooperativity of phosphoenolpyruvate (PEP) binding, ML083 enhances PK-M2 activity, making it a valuable tool for studying tumor metabolism. This compound is essential for research applications focusing on cancer biology and metabolic regulation within tumor cells.
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