Fig. 1 · Structure

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ML 086

PHOSPHO1 Phosphatase Inhibitor

ML 086 is a selective inhibitor of PHOSPHO1 phosphatase, demonstrating an IC50 value of 0.14 μM. This compound is particularly relevant for the investigation of hereditary vascular calcification disorders, such as generalized arterial calcification of infancy, and conditions involving spinal ligament ossification. Its specificity makes it a valuable tool for elucidating the biochemical mechanisms underlying these diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1177148-36-5
Applications PHOSPHO1 Phosphatase Inhibitor
Formula C16H14N2O2S
Molecular Weight 298.36
SMILES
O=C(N(C)C)C1=CC=CC(N2SC3=C(C=CC=C3)C2=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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