Fig. 1 · Structure
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ML 10302
5-HT4 Agonist
ML 10302 is a potent 5-HT4 receptor agonist with a Ki value of 1.07 nM. This compound enhances gut motility by stimulating cholinergic pathways, leading to significant prokinesia in both the small intestine and colon. Additionally, ML 10302 holds potential for research applications in neurological diseases, providing insights into therapeutic mechanisms targeting the gastrointestinal and nervous systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 148868-55-7 |
| Applications | 5-HT4 Agonist |
| Formula | C15H21ClN2O3 |
| Molecular Weight | 312.79 |
| SMILES | O=C(OCCN1CCCCC1)C2=CC(Cl)=C(N)C=C2OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.