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Biological Activity
ML-792 is a potent and selective SAE inhibitor with nanomolar potency in cellular assays. ML-792 selectively blocks SAE enzyme activity and total SUMOylation, thus decreasing cancer cell proliferation.
| In vitro | DMSO | 90 mg/mL (163.22 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.13 mL | 90.67 mL | 181.35 mL |
| 0.5 mM | 3.63 mL | 18.13 mL | 36.27 mL |
| 1 mM | 1.81 mL | 9.07 mL | 18.13 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.63 mL |
*The above data is based on the productmolecular weight 551.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16832 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1644342-14-2 |
| Formula | C21H23BrN6O5S |
| M. Wt | 551.42 |
| Purity | >98% |
| Synonyms | ML 792, ML792 |
| SMILES | O=S(OC[[email protected]@H]1[[email protected]@H](O)C[[email protected]](NC2=NC=NC=C2C(C3=NN(CC4=CC=CC(Br)=C4)C=C3)=O)C1)(N)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
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