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ML165

aIIbb3 Receptor Antagonist

ML165 is an αIIbβ3 receptor antagonist that exerts its effects through orthosteric inhibition at the RGD binding domain. This compound effectively inhibits platelet adhesion to fibrinogen and reduces platelet aggregation, with an IC50 of 96 nM. ML165 is suitable for research applications focused on thrombosis, platelet function, and vascular biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	1355454-05-5
Applications	aIIbb3 Receptor Antagonist
Formula	C₁₇H₁₉N₇O₂S
Molecular Weight	385.44
Synonyms	RUC-2
SMILES	O=C(NC1=CC=CC(C(S2)=NN(C2=NC(N3CCNCC3)=C4)C4=O)=C1)CN

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.