Fig. 1 · Structure

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ML175

GSTO1-1 Inhibitor

ML175 is a selective inhibitor of glutathione transferase Omega 1-1 (GSTO1-1). This compound has been shown to significantly activate Akt and MEK1/2 kinases, which are key signaling molecules involved in cell proliferation and survival. ML175 is primarily utilized in the study of neurodegenerative diseases, including Parkinson's disease, to explore its potential therapeutic effects and underlying mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 610263-01-9
Applications GSTO1-1 Inhibitor
Formula C13H13ClF3N3O4
Molecular Weight 367.71
SMILES
O=C(NCCCN(C(CCl)=O)C1=CC=C([N+]([O-])=O)C=C1)C(F)(F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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