Fig. 1 · Structure
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ML243
CSCs Inhibitor
ML243 is a selective small-molecule inhibitor targeting breast cancer stem cells (CSCs). It exhibits a 32-fold greater inhibitory effect on the CSC-like cell line HMLE_shECad compared to the control line HMLE_shGFP. ML243 is proposed to interact with the Wnt signaling pathway at the protein level, while not affecting RNA expression levels. This compound holds potential for research applications aimed at understanding and targeting CSCs in breast cancer therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1426576-80-8 |
| Applications | CSCs Inhibitor |
| Formula | C14H16N2OS |
| Molecular Weight | 260.35 |
| SMILES | CCC1=CC=C(/C=C/C(NC2=NCCS2)=O)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.