Fig. 1 · Structure
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ML307
Ubc13 Inhibitor
ML307 is a potent inhibitor of the Ubc13 enzyme, demonstrating sub-micromolar activity with an IC50 of 781 nM. This first-in-class compound is suitable for research focused on immunomodulation and inflammation. Its unique mechanism of action provides valuable insights into the regulation of ubiquitin signaling pathways, making it a valuable tool for studies in cellular response and disease mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3058650-52-2 |
| Applications | Ubc13 Inhibitor |
| Formula | C28H36ClN7O |
| Molecular Weight | 522.08 |
| SMILES | O=C(NCC1CCN(CC2=CC(Cl)=CC=C2)CC1)[C@@H]3CCCN(C4=NC=NC5=C4N=C6CCCCN65)C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.