Fig. 1 · Structure
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ML336
VEEV Inhibitor
ML336 is a quinazolinone-based inhibitor specifically targeting Venezuelan equine encephalitis virus (VEEV). It demonstrates significant potency against VEEV-induced cytopathic effects, exhibiting IC50 values of 32, 20, and 42 nM for VEEV TC-83, VEEV V3526, and wild type CPE, respectively. This compound is valuable for research applications associated with VEEV and related viral pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1613465-33-0 |
| Applications | VEEV Inhibitor |
| Formula | C19H21N5O3 |
| Molecular Weight | 367.40 |
| SMILES | O=C(NC1=CC=CC=C1)C2=CC([N+]([O-])=O)=CC=C2/N=C3N(C)CCN(C)C/3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.