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ML349 is a potent and specific acyl protein thioesterase 2 (APT-2) inhibitor with a Ki of 120 nM. ML349 is also an inhibitor of LYPLA2 with an IC50 of 144 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22 mL | 110 mL | 219.99 mL |
| 0.5 mM | 4.4 mL | 22 mL | 44 mL |
| 1 mM | 2.2 mL | 11 mL | 22 mL |
| 5 mM | 0.44 mL | 2.2 mL | 4.4 mL |
*The above data is based on the productmolecular weight 454.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12301 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 890819-86-0 |
| Formula | C23H22N2O4S2 |
| M. Wt | 454.56 |
| Purity | >98% |
| Synonyms | ML 349, ML-349 |
| SMILES | COC1=CC=C(N2CCN(C(C3=CC4=C(C(C=CC=C5)=C5S(C4)(=O)=O)S3)=O)CC2)C=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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