ML349

Catalog No.: A12301

APT-2 inhibitor

ML349

ML349 Chemical Structure

CAS NO. 890819-86-0

ML349 is a potent and specific acyl protein thioesterase 2 (APT-2) inhibitor with a Ki of 120 nM. ML349 is also an inhibitor of LYPLA2 with an IC50 of 144 nM.

Availability: In stock

Package Price Qty
5 mg
$126.00
10 mg
$217.00
50 mg
$644.00
100 mg
$1,288.00
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Biological Activity

ML349 is a potent and specific acyl protein thioesterase 2 (APT-2) inhibitor with a Ki of 120 nM. ML349 is also an inhibitor of LYPLA2 with an IC50 of 144 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22 mL 110 mL 219.99 mL
0.5 mM 4.4 mL 22 mL 44 mL
1 mM 2.2 mL 11 mL 22 mL
5 mM 0.44 mL 2.2 mL 4.4 mL

*The above data is based on the productmolecular weight 454.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12301
Actions Inhibitor
CAS No. 890819-86-0
Formula C23H22N2O4S2
M. Wt 454.56
Purity >98%
Synonyms ML 349, ML-349
SMILES COC1=CC=C(N2CCN(C(C3=CC4=C(C(C=CC=C5)=C5S(C4)(=O)=O)S3)=O)CC2)C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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