Fig. 1 · Structure
Documents & Downloads
ML356
FAS Inhibitor
ML356 is a selective inhibitor of fatty acid synthase (FAS), targeting the thioesterase domain with an IC50 of 0.334 μM. This compound effectively disrupts de novo palmitate synthesis in PC-3 cells, exhibiting an IC50 of 20 μM. ML356 demonstrates favorable membrane permeability and stability in both human and mouse plasma, making it a valuable tool for research into metabolic disorders and cancer biology.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1808260-45-8 |
| Applications | FAS Inhibitor |
| Formula | C19H25N3O4S2 |
| Molecular Weight | 423.55 |
| SMILES | O=C(C(CC)CC)NC1=NC(C2=CC=C(S(=O)(N3CCOCC3)=O)C=C2)=CS1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.