Fig. 1 · Structure
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ML359
PDI Inhibitor
ML359 is a selective and reversible inhibitor of protein disulfide isomerase (PDI), with an IC50 of 250 nM. This compound effectively disrupts PDI activity, leading to an inhibition of thrombus formation in vivo. ML359 is valuable in research related to cardiovascular diseases and the modulation of protein folding processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1069858-99-6 |
| Applications | PDI Inhibitor |
| Formula | C23H28ClNO4 |
| Molecular Weight | 417.93 |
| SMILES | O=C(C1(CCN(CC1)CC2=CC=C(C(Cl)=C2)O)CCOC3=CC=CC=C3)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.