Fig. 1 · Structure

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ML377

Triacylglyceride Accumulation Inhibitor

ML377 is a selective triacylglyceride accumulation inhibitor targeting lipid metabolism. Exhibiting an IC50 of 1.1 μM, this compound is useful in research focused on understanding lipid dysregulation and exploring therapeutic strategies for metabolic disorders. Its ability to modulate triacylglyceride levels makes it a valuable tool in studies related to obesity and associated conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2650088-70-1
Applications Triacylglyceride Accumulation Inhibitor
Formula C26H24N4O3
Molecular Weight 440.49
SMILES
O=C(C1=CC=CC(CN2CCOCC)=C1C2=O)NC3=CC=CC(C4=NC5=CC=CC=C5N4)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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