Fig. 1 · Structure

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ML388

HPGD Inhibitor

ML388 is a potent and selective inhibitor of hydroxyprostaglandin dehydrogenase (HPGD), showcasing an IC50 value of 34 nM. This compound is known to elevate prostaglandin E2 (PGE2) levels in A549 lung carcinoma cells and LNCaP prostate cancer cells, making it a valuable tool for studying prostaglandin synthesis and signaling pathways. ML388 is of particular interest in cancer research and the investigation of inflammatory processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1537192-31-6
Applications HPGD Inhibitor
Formula C20H24N4
Molecular Weight 320.43
SMILES
CC1=CC=C(C=C1)N2C(C)=C(C=C2C)C3=NN=C4N3CCCCC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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