Fig. 1 · Structure

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ML389

V1a Receptor Antagonist

ML389 is a highly selective V1a receptor antagonist, displaying an IC50 value of 40 nM. This compound demonstrates significant potential in the research of central nervous system disorders, including anxiety, depression, and post-traumatic stress disorder (PTSD). Its ability to effectively inhibit the V1a receptor may contribute to advanced studies in neuropharmacology and therapeutic targeting.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 1622294-25-0
Applications V1a Receptor Antagonist
Formula C21H23Cl2N3O
Molecular Weight 404.33
SMILES
O=C(C1CCN(C2=NC=C(Cl)C=C2)CC1)N(C3=CC=C(Cl)C=C3)CC4CC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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