Fig. 1 · Structure
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MLAF50
REV1 UBM2-Ubiquitin Interaction Inhibitor
MLAF50 is a potent inhibitor of the REV1 UBM2-ubiquitin interaction. It effectively disrupts the chromatin co-localization of REV1 and PCNA upon DNA damage, thereby influencing DNA repair pathways. This compound is valuable for research applications investigating the mechanisms of fidelity in DNA replication and repair processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1417653-96-3 |
| Applications | REV1 UBM2-Ubiquitin Interaction Inhibitor |
| Formula | C15H12I2O4 |
| Molecular Weight | 510.06 |
| SMILES | O=C(O)CCC1=CC=C(I)C(OC2=CC=C(O)C=C2)=C1I |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.