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MLKL-IN-1

MLK Inhibitor

MLKL-IN-1 is a covalent inhibitor targeting mixed lineage kinase domain-like protein (MLKL) with a KD of 50 μM. This compound plays a critical role in the inhibition of necroptosis, a form of regulated cell death implicated in various pathological conditions. MLKL-IN-1 is valuable for research applications focused on cell death pathways, inflammation, and potential therapeutic interventions in diseases associated with necroptosis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2837019-30-2
Applications	MLK Inhibitor
Formula	C₁₉H₂₀N₂O₃
Molecular Weight	324.37
SMILES	OC(C1=CC=C(N=C([C@@H](OC)C2=CC=C(C(C)C)C=C2)N3)C3=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.