Fig. 1 · Structure
Documents & Downloads
MLKL-IN-2
MLKL Inhibitor
MLKL-IN-2 is a potent inhibitor of Mixed Lineage Kinase Domain-Like Pseudokinase (MLKL), a key executor of necroptosis. By selectively inhibiting MLKL, this compound plays a critical role in studying necroptosis pathways and their implications in various disease states, including neurodegenerative disorders and cancer. Researchers can utilize MLKL-IN-2 to elucidate the biological mechanisms and therapeutic potential of targeting necroptotic pathways in inflammation and cell death.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 899759-16-1 |
| Applications | MLKL Inhibitor |
| Formula | C26H25N5O |
| Molecular Weight | 423.51 |
| SMILES | O=C(C1=CC=C2C=CC=CC2=C1)NC3=CC=CC(C4=NN=C(N5CCN(C)CC5)C=C4)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.