Fig. 1 · Structure
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MLKL-IN-5
MLKL Inhibitor
MLKL-IN-5 is a selective inhibitor of mixed lineage kinase domain-like protein (MLKL), a key mediator of necroptosis. This compound effectively disrupts MLKL's function, thereby preventing necroptotic cell death. MLKL-IN-5 is utilized in research investigating the mechanisms of necroptosis and its implications in various diseases, including neurodegenerative disorders and cancer.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2755872-58-1 |
| Applications | MLKL Inhibitor |
| Formula | C18H20N6O4S |
| Molecular Weight | 416.45 |
| SMILES | O=C(C1=C(NC2=NC(OC)=CC=C2)NN=C1C3=CC=C(NS(=O)(CC)=O)C=C3)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.