MLN 0905

Catalog No.: A12429

PLK1 inhibitor

MLN 0905

MLN 0905 Chemical Structure

CAS NO. 1228960-69-7

MLN0905 is a potent, selective small-molecule PLK1 inhibitor. MLN0905 inhibits cell proliferation in a broad range of human tumor cells including DLBCL cell lines.

Availability: In stock

Package Price Qty
5 mg
$130.00
10 mg
$240.00
25 mg
$385.00
100 mg
$1,200.00
10mM * 1mL in DMSO
$198.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

MLN0905 is a potent, selective small-molecule PLK1 inhibitor. MLN0905 inhibits cell proliferation in a broad range of human tumor cells including DLBCL cell lines.
Targets
PLK1
2 nM
In vitro DMSO 97 mg/mL (199.35 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.55 mL 102.76 mL 205.52 mL
0.5 mM 4.11 mL 20.55 mL 41.1 mL
1 mM 2.06 mL 10.28 mL 20.55 mL
5 mM 0.41 mL 2.06 mL 4.11 mL

*The above data is based on the productmolecular weight 486.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12429
Actions Inhibitor
M. Wt 486.56
Formula C24H25F3N6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1228960-69-7
Synonyms MLN-0905,MLN0905
SMILES CC1=C(C=C(C=N1)CCCN(C)C)NC2=NC=C3CC(=S)NC4=C(C3=N2)C=CC(=C4)C(F)(F)F

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