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MLN0905 is a potent, selective small-molecule PLK1 inhibitor. MLN0905 inhibits cell proliferation in a broad range of human tumor cells including DLBCL cell lines.
Targets
| PLK1 | ||||
| 2 nM |
| In vitro | DMSO | 97 mg/mL (199.35 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.55 mL | 102.76 mL | 205.52 mL |
| 0.5 mM | 4.11 mL | 20.55 mL | 41.1 mL |
| 1 mM | 2.06 mL | 10.28 mL | 20.55 mL |
| 5 mM | 0.41 mL | 2.06 mL | 4.11 mL |
*The above data is based on the productmolecular weight 486.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A12429 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 486.56 |
| Formula | C24H25F3N6S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1228960-69-7 |
| Synonyms | MLN-0905,MLN0905 |
| SMILES | CC1=C(C=C(C=N1)CCCN(C)C)NC2=NC=C3CC(=S)NC4=C(C3=N2)C=CC(=C4)C(F)(F)F |
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Contact information
United StatesAdooq Bioscience
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Email: [email protected]
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