MLN-4760

Catalog No.: A16884

ACE2 inhibitor

MLN-4760

MLN-4760 Chemical Structure

CAS NO. 305335-31-3

MLN-4760 is an angiotensin-converting (ACE2) inhibitor. In huMNCs, MLN-4760-B detected 63% ACE2 with 28-fold selectivity over ACE.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$680.00
50 mg
$2,800.00
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Warning WARNING: Attention California Residents: This product can expose you to chemicals including MLN-4760 , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

MLN-4760 is an angiotensin-converting (ACE2) inhibitor. In huMNCs, MLN-4760-B detected 63% ACE2 with 28-fold selectivity over ACE.
In vitro DMSO Insoluble
Water 83 mg/mL (193.78 mM)
Ethanol 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.35 mL 116.74 mL 233.48 mL
0.5 mM 4.67 mL 23.35 mL 46.7 mL
1 mM 2.33 mL 11.67 mL 23.35 mL
5 mM 0.47 mL 2.33 mL 4.67 mL

*The above data is based on the productmolecular weight 428.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16884
Actions Inhibitor
CAS No. 305335-31-3
Formula C19H23Cl2N3O4
M. Wt 428.31
Purity >98%
Synonyms MLN 4760, MLN4760
SMILES CC(C)C[[email protected]](N[[email protected]@H](CC1=CN=CN1CC2=CC(Cl)=CC(Cl)=C2)C(O)=O)C(O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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