MLN3126

Name: MLN3126
Brand: Adooq Bioscience
SKU: A59528
Rating: 5 (288 reviews)

Catalog No.: A59528

CCR9 Antagonist

MLN3126 is a potent CCR9 antagonist that exhibits significant oral bioavailability. It effectively inhibits CCL25-induced calcium mobilization and the chemotaxis of mouse primary thymocytes, demonstrating an IC50 value of 6.3 nM for calcium influx. This compound is valuable for research applications investigating immune cell trafficking and related pathways in inflammatory conditions.

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Grouped product items
Size	Price	Stock
5mg	$205.00	In stock
10mg	$335.00	In stock
25mg	$715.00	In stock
50mg	$920.00	In stock
100mg	$1,290.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	MLN3126 is a potent CCR9 antagonist that exhibits significant oral bioavailability. It effectively inhibits CCL25-induced calcium mobilization and the chemotaxis of mouse primary thymocytes, demonstrating an IC50 value of 6.3 nM for calcium influx. This compound is valuable for research applications investigating immune cell trafficking and related pathways in inflammatory conditions.

Product Information

Catalog Num	A59528
Formula	C21H19ClN2O5S
Molecular Weight	446.90
CAS Number	628300-71-0
SMILES	O=S(C1=CC=C(OC(C)C)C=C1)(NC2=CC=C(Cl)C=C2C(C3=CC=[N+]([O-])C=C3)=O)=O

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