MLN8054

Catalog No.: A10601
Aurora A Inhibitor
MLN8054 is an inhibitor of Aurora A kinase, induces senescence in human tumor cells both in vitro and in vivo.
Grouped product items
Size Price Stock Qty
1mg
$40.00
In stock
2mg
$60.00
In stock
5mg
$75.00
In stock
10mg
$105.00
In stock
25mg
$240.00
In stock
50mg
$375.00
In stock
100mg
$555.00
In stock
10mM * 1mL in DMSO
$75.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Adooq Products cited in reputable paper
Biological Activity
Discription MLN8054 is an inhibitor of Aurora A kinase, induces senescence in human tumor cells both in vitro and in vivo.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A10601
Formula C25H15ClF2N4O2
Molecular Weight 476.9
CAS Number 869363-13-3
SMILES C1C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)C(=N1)C4=C(C=CC=C4F)F)NC5=CC=C(C=C5)C(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 91 mg/mL (190.82 mM)
Water Insoluble
Ethanol Insoluble
In vivo 15% Captisol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.97 mL 104.84 mL 209.69 mL
0.5 mM 4.19 mL 20.97 mL 41.94 mL
1 mM 2.1 mL 10.48 mL 20.97 mL
5 mM 0.42 mL 2.1 mL 4.19 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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