Fig. 1 · Structure
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MLS-0437605
DUSP3 Inhibitor
MLS-0437605 is a selective inhibitor of dual-specificity phosphatase 3 (DUSP3) with an IC50 of 3.7 μM. It demonstrates a higher selectivity for DUSP3 compared to DUSP22 and other protein tyrosine phosphatases. This compound is valuable for research applications focusing on the regulation of MAPK signaling pathways and the role of DUSP3 in various biological processes, including cancer and inflammation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 862975-18-6 |
| Applications | DUSP3 Inhibitor |
| Formula | C16H11FN4O2S |
| Molecular Weight | 342.35 |
| SMILES | COC1=CC=C(C2=NN=C(NC3=NC4=C(F)C=CC=C4S3)O2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.