MM-401 is a potent inhibitor of MLL1, a methyltransferase that targets H3K4. By interfering with the MLL1-WDR5 interaction, MM-401 effectively inhibits MLL1 activity with an IC50 of 0.32 μM. This compound has been shown to induce cell cycle arrest, promote apoptosis, and facilitate differentiation. MM-401 is particularly relevant for research focused on MLL leukemia.
MM-401 is a potent inhibitor of MLL1, a methyltransferase that targets H3K4. By interfering with the MLL1-WDR5 interaction, MM-401 effectively inhibits MLL1 activity with an IC50 of 0.32 μM. This compound has been shown to induce cell cycle arrest, promote apoptosis, and facilitate differentiation. MM-401 is particularly relevant for research focused on MLL leukemia.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
