Fig. 1 · Structure
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MM3122
TMPRSS2 Inhibitor
MM3122 is a selective inhibitor of the type II transmembrane serine protease (TMPRSS2), exhibiting a potent IC50 value of 0.34 nM. By effectively blocking TMPRSS2, MM3122 inhibits the entry of SARS-CoV-2 and MERS-CoV into human cells. This compound serves as a valuable tool for studying viral entry mechanisms and developing therapeutic strategies against these coronaviruses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2574390-27-3 |
| Applications | TMPRSS2 Inhibitor |
| Formula | C31H39N9O6S |
| Molecular Weight | 665.76 |
| SMILES | CC(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(C2=NC3=CC=CC=C3S2)=O)=O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.